Strobilanthes crispus (L.) Blume (S. crispus) is distributed throughout the regions of Madagascar to the Malay Archipelago (Figure 1). The effect of Strobilanthes crispus extract and glycyrrhizin in on rats induced with carcinoma is reported. Anticancer effects of Strobilanthes crispus in experimental breast cancer. The cancer group was continued on 10 % Tween-20 feeding for 8 weeks. There are two major phases of inflammatory effects i.e. Strobilanthes crispus has been traditionally used as antidiabetic, anticancer, diuretic, antilytic and laxative agent. Universiti Sains Malaysia, Malaysia Keynote: Allied J Med Res. The non-selectiveness of compounds may impose severe side effects on patients with cancer, ... Chong HZ, Rahmat A, Yeap SK, Akim Md A, Alitheen NB, Othman F, Gwendoline-Ee CL. Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon Strobilanthes cripus was able to reduce cell viability and proliferation in MTT and BrdU assays. However, cytotoxicity and antiproliferative effect of S. crispus is still unclear. In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. BMC Complement Altern Med. }, author={F. Hussin and S. Eshkoor and A. Rahmat and F. Othman and A. Akim and Z. Eshak}, journal={Asian Pacific journal of cancer prevention : APJCP}, year={2015}, volume={16 14}, pages={ 6047-53 } } Five groups of rats were injected subcutaneously with AOM, 15 mg/kg body weight, each once weekly for 2 weeks. In particular, S. crispus subfraction (SCS) significantly reduced tumor growth in N-methyl-N-Nitrosourea-induced breast cancer rat model. Uses, Benefits, Cures, Side Effects, Nutrients in Strobilanthes Cuspidata. Anticancer activity of a sub-fraction of dichloromethane extract of Strobilanthes crispus on human breast and prostate cancer cells in vitro Nik Soriani Yaacob,1 Nurraihana Hamzah,2 Nik Nursyazni Nik Mohamed Kamal,1 Siti Amalina Zainal Abidin,1 Choon Sheen Lai,2 Visweswaran Navaratnam,2 and Mohd Nor Norazmi3 1Department … It is commonly consumed in the form of herbal tea. Strobilanthes crispus is a traditional remedy for many ailments including cancer. Cancer patients seek alternative remedies such as traditional medicinal plants for safe and effective treatment and help overcome the side effects of conventional therapy. The standard drug group was continued on 35 mg/kg 5-fluorouracil … Strobilanthes crispus is a traditional remedy for many ailments including cancer. oxide; Strobilanthes crispus . Anticancer effects of Strobilanthes crispus in experimental breast cancer Limited efficacy and concerns over toxicity of chemotherapeutic drugs have contributed to the worldwide increase in the use of herbal products by cancer patients. Nik Soriani Yaacob. Current knowledge indicates that extracts of Strobilanthes crispus of the Acanthaceae family exhibit potent anticancer properties in vitro and are non-toxic in vivo. In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. The aim was to study the antioxidant and chemopreventive effects of Strobilanthes crispus on colorectal cancer formation. It is also known in a Malay name as “Pecah Beling” or “Keji Beling” in Indonesia. INTRODUCTION Inflammation describes as the any defensive response by body towards foreign particles, injuries and cellular damage. … many side effects. Natural products have always been an unrivalled source of anticancer therapeutics due to their seemingly compatible biological activities. Cells were seeded in 96-well plates at a density of 10 5 and treated for 24, 48 and 72 hr. S. crispus is considered a traditional medicine and used as an Strobilanthes crispus (S. crispus), is a Malaysian herb locally known as ‘Pecah kaca’ or ‘Jin batu’ which have demonstrated potent anticancer effects in both in vitro and in vivo models. How Strobilanthes Cuspidata is effective for various diseases is listed in repertory format. ResearchGate: Strobilanthes crispus. MCF-7 and MDA-MB-231 Cell Cycle Modulation by Strobilanthes crispus and its Combination with Tamoxifen Asian Pac J Cancer Prev, 16 (18), 8135-8140 Introduction Many cancer patients seek traditional therapeutic medicines with the hope of enhancing their cancer therapy while minimizing side effects. 2006. Effect of Strobilanthes crispus extract and individual polyphenols on lipolysis Author: Zawawi, Norhasnida ... the high cost and potentially hazardous side-effects of anti-obesity drugs have led many researchers to turn to naturally occurring compounds obtained from fruits, vegetables, herbs and plants for the treatment of obesity. Methods . @article{Hussin2015StrobilanthesCJ, title={Strobilanthes crispus Juice Concentrations and Anticancer Effects on DNA Damage, Apoptosis and Gene Expression in Hepatocellular Carcinoma Cells. Strobilanthes crispus is also known as pecah beling, pecah kaca, bayam karang or jin batu in Malaysia. Natural cancer treatment with the use of natural products plays a relevant role in cancer therapy today as they have minimal side effects and capable of reducing the side effects caused by synthetic drugs (Ho, 2015). was to study the antioxidant and chemopreventive effects of Strobilanthes crispus on colorectal cancer formation. Its purported anticancer effects have led to the commercialization of the plant leaves as medicinal herbal tea, although the scientific basis for its use has not been established. Fadzelly AM, Asmah R, Fauziah O. List of various diseases cured by Strobilanthes Cuspidata. acute phase and chronic phase. The Black Face General has been in the limelight in recent years for its anti-cancer properties. Mid-dorsal linear incisions of 2 cm in length were made on each animal. Black Face General (黑面将军) is botanically known as Strobilanthes crispus (L.) Blume and is a member of the Acanthaceae family. Current knowledge indicates that extracts of Strobilanthes crispus of the Acanthaceae family exhibit potent anticancer properties in vitro and are non-toxic in vivo. Hair on the dorsal side of rats was shaved and the skin was cleaned with 70% alcohol. In vitro cytotoxicity of Strobilanthes crispus ethanol extract on hormone dependent human breast adenocarcinoma MCF-7 cell. View Article: Google Scholar. Int J Cancer Res. The cancer group was continued on 10 % Tween-20 feeding for 8 weeks. 2:152–158. Anticancer effects of Strobilanthes crispus in experimental breast cancer. Its purported anticancer effects have led to the commercialization of the plant leaves as medicinal herbal tea, although the scientific basis for its use has not been established. Introduction. Effects of strobilanthes crispus extract on the apoptotic pathway of human liver carcinoma cell lines Susi Endrini , Suherman 2, Asmah Rahmat3, Patimah Ismail4, Y.H. 1. Traditionally known as 'pecah beling' or 'pecah kaca', the leaves of this plant are boiled with water and used in folk medicine for their antidiabetic, diuretic, anticancer and blood pressure lowering properties [ 12 , 13 ]. Effects of Strobilanthes crispus tea aqueous extracts on glucose and lipid profile in normal and streptozotocin-induced hyperglycemic rats. Strobilanthes crispus (Acanthaceae) has been used traditionally as antidiabetic, diuretic, antilytic, and laxative and has been proven scientifically to possess high antioxidant activity, anti-AIDS, and anticancer properties. 2012; 12:35. doi: 10 .1186/1472-6882-12 … S. However, the high cost and potentially hazardous side-effects of anti-obesity drugs have led many researchers to turn to naturally occurring compounds obtained from fruits, vegetables, herbs and plants for the treatment of obesity. Request PDF | Effect of Strobilanthes crispus extract and individual polyphenols on lipolysis | Obesity is a disease that has reached epidemic proportions across the world. Effects of Strobilanthes crispus extract (IC 50 concentration = 30 μg/mL) on cell proliferation of MCF-7 breast cancer cell lines. The first part of this study evaluated the effect of S. Treatment with glycyrrhizin caused decrease in liver GST activity compared to control. Methods: Five groups of rats were injected subcutaneously with AOM, 15 mg/kg body weight, each once weekly for 2 weeks. Values are presented as means (n = … The results showed significant, increase of liver microsome glutathione s-transferase (GST) in rats after 12 weeks. I. 3 rd International Conference and Expo on Herbal & Alternative Medicine September 01-02, 2017 London, UK. International Food Research Journal: Phytochemistry, pharmacology and toxicology properties of Strobilanthes crispus. Strobilanthes crispus Blume is traditionally consumed among local Malay and indigenous communities for the treatment of cancer and other ailments such… Chemo/Radiation Side Effects Contact me Links Strobilanthes crispus. The non-selectiveness of compounds may impose severe side effects on patients with cancer, ... Antiproliferative properties and antioxidant activity of various types of Strobilanthes crispus tea. Cancer patients seek alternative remedies such as traditional medicinal plants for safe and effective treatment and help overcome the side effects of conventional therapy. Strobilanthes crispus leaves extracts (SCE) induced lipolysis and increased leptin level in diet-induced obese rats fed high-fat diet Abstract The aim of the present study was to assess the anti-obesity and lipolysis effects of Strobilanthes crispus leaves extract (SCE) in diet-induced obese (DIO) rats by administering 1% (w/w) of SCE in drinking water. Strobilanthes crispus (Family: Acanthaceae) (S. crispus), or locally known as Pecah Kaca in Malaysia, has gained great attention due to its high medicinal values,.It is also known as “daun picah beling” in Jakarta and “enyoh kelo”, “kecibeling”, “ngokilo” in Java.The leaves of this plant are oblong-lanceolate, rather obtuse, and shallowly crenate-crispate. 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